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Chimeric Allo-Antigen Receptors (CALLARs) directed to Factor VIII autoantibodies
Market NeedHemophilia A is an inherited X-linked disease caused by Factor VIII (FVIII) deficiency and is a life-threatening bleeding disorder. The disease is associated with frequent hemarthosis and arthropathy that causes significant morbidity for patients. Factor replacement therapy using recombinant human FVIII (rhFVIII) is the standard of care for...
Published: 8/5/2019   |   Inventor(s): Valder Arruda, Sarah Richman, Benjamin Samelson-Jones, Michael Milone
Category(s): Therapeutic