Latest technologies from The Children's Hospital of Philadelphiahttp://technologytransfer.research.chop.eduBe the first to know about the latest inventions and technologies available from The Children's Hospital of Philadelphiaen-USTue, 20 Nov 2018 21:39:37 GMTMon, 09 Jul 2018 11:29:51 GMThttp://blogs.law.harvard.edu/tech/rssInventions@email.chop.eduCopyright 2018, The Children's Hospital of PhiladelphiaImproved Blood Transfusion Screening with iPSC-derived Reagentshttp://technologytransfer.research.chop.edu/technology/28051Mon, 09 Jul 2018 11:29:51 GMTInventions@email.chop.eduhttp://technologytransfer.research.chop.edu/technology/28051Optimized discovery of tumor specific antigens for neuroblastoma immunotherapyhttp://technologytransfer.research.chop.edu/technology/28050Mon, 09 Jul 2018 11:06:58 GMTInventions@email.chop.eduhttp://technologytransfer.research.chop.edu/technology/28050Quantitative phenotyping to automate diagnosis of autism spectrum disorder (ASD)http://technologytransfer.research.chop.edu/technology/28049Mon, 09 Jul 2018 10:58:58 GMTInventions@email.chop.eduhttp://technologytransfer.research.chop.edu/technology/28049Malabsorption Blood Test Extension Beyond Pancreatic Based Diagnosishttp://technologytransfer.research.chop.edu/technology/27711Wed, 16 May 2018 11:32:06 GMTInventions@email.chop.eduhttp://technologytransfer.research.chop.edu/technology/27711PHRASE (Public Health Rules Assessment Support Engine)http://technologytransfer.research.chop.edu/technology/27220Tue, 27 Feb 2018 13:46:49 GMTInventions@email.chop.eduhttp://technologytransfer.research.chop.edu/technology/27220Factor IX Variants With Enhanced Biological Functionshttp://technologytransfer.research.chop.edu/technology/27219Tue, 27 Feb 2018 13:44:57 GMTInventions@email.chop.eduhttp://technologytransfer.research.chop.edu/technology/27219Chimeric Allo-Antigen Receptors (CALLARs) directed to Factor VIII autoantibodieshttp://technologytransfer.research.chop.edu/technology/27218Market NeedHemophilia A is an inherited X-linked disease caused by Factor VIII (FVIII) deficiency and is a life-threatening bleeding disorder. The disease is associated with frequent hemarthosis and arthropathy that causes significant morbidity for patients. Factor replacement therapy using recombinant human FVIII (rhFVIII) is the standard of care for patients with hemophilia A. Unfortunately, 10-40% of patients with hemophilia develop antibodies (alloantibodies) to plasma-derived or recombinant human FVIII protein that inhibits the recombinant FVIII function. The consequences of allow antibod...Tue, 27 Feb 2018 13:44:10 GMTInventions@email.chop.eduhttp://technologytransfer.research.chop.edu/technology/27218Methods For The Generation Of Self Renewing Endodermal Precursor Populations Derived From Human Embryonic Stem Cells And Induced Pluripotent Stem Cellshttp://technologytransfer.research.chop.edu/technology/27217Market NeedCell-based therapies for disease of endodermally derived organs such as the liver, pancreas, and intestines have gained significant interest. In addition to cell-based treatment strategies, there is a proven value in screening drugs in cellular models of the organ systems during development process. Commonly this screening is performed on induced pluripotent stem cells that require a complex and lengthy process to create a differentiated cell type from these cells for each screen. There is a need for a simpler method to create endodermal progenitor cells for both treatment and scree...Tue, 27 Feb 2018 13:42:39 GMTInventions@email.chop.eduhttp://technologytransfer.research.chop.edu/technology/27217Discovery Of Novel CVID Loci Using The Exome SNP Chip Platformhttp://technologytransfer.research.chop.edu/technology/27216Tue, 27 Feb 2018 13:41:29 GMTInventions@email.chop.eduhttp://technologytransfer.research.chop.edu/technology/27216Genome- And Phenome-Wide Association Analyses Uncovers MET as a Susceptibility Gene of Cerebral Palsyhttp://technologytransfer.research.chop.edu/technology/27215Tue, 27 Feb 2018 13:40:47 GMTInventions@email.chop.eduhttp://technologytransfer.research.chop.edu/technology/27215AAV-Mediated GRN Gene Delivery For Therapy Of Frontotemporal Dementia Due To Progranulin Mutationshttp://technologytransfer.research.chop.edu/technology/27214Tue, 27 Feb 2018 13:39:57 GMTInventions@email.chop.eduhttp://technologytransfer.research.chop.edu/technology/27214Gene-Editing Of FMR1 Using CRISPR/Cas9http://technologytransfer.research.chop.edu/technology/27213Market NeedFragile X syndrome is an X-chromosome-linked disease that affects males more severely than females and is the most common cause of inherited intellectual disability, often co-occurring with Autism spectrum disorder. According to the CDC, around 1 in every 6000 males and 7000 females are born with the condition. Patients usually present with delay in reaching early language and communication milestones, lower than average intelligence quotient that declines with age, attention problems, anxiety, self-injury, hypersensitivity, and aggressiveness. Genetically, the disease is caused by ...Tue, 27 Feb 2018 13:39:03 GMTInventions@email.chop.eduhttp://technologytransfer.research.chop.edu/technology/27213Allele Specific Genome Editing For Huntington's Disease Therapyhttp://technologytransfer.research.chop.edu/technology/27212Tue, 27 Feb 2018 13:37:59 GMTInventions@email.chop.eduhttp://technologytransfer.research.chop.edu/technology/27212Repurpose PARP-1 Inhibitors for Type 2 Diabetes and Cystic Fibrosis Related Diabeteshttp://technologytransfer.research.chop.edu/technology/25257Wed, 10 May 2017 09:02:07 GMTInventions@email.chop.eduhttp://technologytransfer.research.chop.edu/technology/25257Efficiently and Clearly Record Genetic Information during Genetic Counseling Sessionshttp://technologytransfer.research.chop.edu/technology/25255Wed, 10 May 2017 08:31:24 GMTInventions@email.chop.eduhttp://technologytransfer.research.chop.edu/technology/25255Detect Mulitple Types of Epithelial Tumors and Determine Cancer Sage with ONe Biomarkerhttp://technologytransfer.research.chop.edu/technology/25251Tue, 09 May 2017 12:15:35 GMTInventions@email.chop.eduhttp://technologytransfer.research.chop.edu/technology/25251Diagnostic Test for Cornelia de Lange Syndrome (CdLS)http://technologytransfer.research.chop.edu/technology/25250Tue, 09 May 2017 12:07:21 GMTInventions@email.chop.eduhttp://technologytransfer.research.chop.edu/technology/25250Metal Surface Compatible Gene Therapyhttp://technologytransfer.research.chop.edu/technology/25249Tue, 09 May 2017 12:00:10 GMTInventions@email.chop.eduhttp://technologytransfer.research.chop.edu/technology/25249Protect Medical Device Implants Against Oxidative Damagehttp://technologytransfer.research.chop.edu/technology/25247Tue, 09 May 2017 11:28:50 GMTInventions@email.chop.eduhttp://technologytransfer.research.chop.edu/technology/25247Continuous, Convenient Lymphatic Drainage Systemhttp://technologytransfer.research.chop.edu/technology/25246Tue, 09 May 2017 10:56:53 GMTInventions@email.chop.eduhttp://technologytransfer.research.chop.edu/technology/25246Detection of HER2 in Urine to Diagnose Lupus Nephritis (LN)http://technologytransfer.research.chop.edu/technology/24170Thu, 23 Feb 2017 04:25:34 GMTInventions@email.chop.eduhttp://technologytransfer.research.chop.edu/technology/24170Platform technology for direct targeting of therapeutics to neuronshttp://technologytransfer.research.chop.edu/technology/24168Thu, 23 Feb 2017 04:21:25 GMTInventions@email.chop.eduhttp://technologytransfer.research.chop.edu/technology/24168Harnessing viral strategies to suppress inflammationhttp://technologytransfer.research.chop.edu/technology/24167Thu, 23 Feb 2017 04:12:39 GMTInventions@email.chop.eduhttp://technologytransfer.research.chop.edu/technology/24167Enhancing platelet production from megakaryocytes in-vitrohttp://technologytransfer.research.chop.edu/technology/24166Thu, 23 Feb 2017 04:05:03 GMTInventions@email.chop.eduhttp://technologytransfer.research.chop.edu/technology/24166Treating B-cell Lymphoma by targeting a cell surface receptorhttp://technologytransfer.research.chop.edu/technology/24165Thu, 23 Feb 2017 04:01:15 GMTInventions@email.chop.eduhttp://technologytransfer.research.chop.edu/technology/24165Specific treatment of Graft Versus Host Disease (GVHD) without affecting graft efficacyhttp://technologytransfer.research.chop.edu/technology/24164Thu, 23 Feb 2017 03:43:24 GMTInventions@email.chop.eduhttp://technologytransfer.research.chop.edu/technology/24164Automated detection of proper endotracheal intubationhttp://technologytransfer.research.chop.edu/technology/24159Wed, 22 Feb 2017 06:06:23 GMTInventions@email.chop.eduhttp://technologytransfer.research.chop.edu/technology/24159Non-invasive biomarker specific for Crohn's disease diagnosishttp://technologytransfer.research.chop.edu/technology/23925Fri, 03 Feb 2017 03:18:41 GMTInventions@email.chop.eduhttp://technologytransfer.research.chop.edu/technology/23925A Gene Therapy Approach to Treat Hepatitis C Virus (HCV) Infectionhttp://technologytransfer.research.chop.edu/technology/23874Wed, 25 Jan 2017 04:41:43 GMTInventions@email.chop.eduhttp://technologytransfer.research.chop.edu/technology/23874