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FACTOR IX VARIANTS WITH ENHANCED BIOLOGICAL FUNCTIONS

Market NeedHemophilia B, also known as Christmas disease, is an x-linked genetic disorder caused by missing or defective Factor IX (FIX), a clotting protein. It is estimated that hemophilia occurs 1 in every 5000 births with 20,000 estimated to have hemophilia in the US alone. The severity of decrease in FIX levels in Hemophilia B patients varies from...

Published: 6/24/2019 | Inventor(s): Valder Arruda, Rodney Camire, Benjamin Samelson-Jones

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Category(s): Therapeutic