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Homology-independent intron targeting (HITI) for scalable tagging of endogenous genes

Efficient and Scalable tagging of endogenous genes Homology-independent intron targeting (HITI) for scalable tagging of endogenous genes Market NeedFusing endogenous proteins with fluorescence or epitope tags is a widely used and essential approach for studying proteins within their natural regulatory context. The advent of CRISPR tools for modifying...

Published: 7/8/2019 | Inventor(s): Ophir Shalem, Yevgeniy Serebrenik, Stephanie Sansbury

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Category(s): Research Tool/Reagent

Improved Blood Transfusion Screening with iPSC-derived Reagents

Red Blood Cell (RBC) Reagents with Rare Antigen Phenotypes for Prevention of Alloimmunization Reaction in SCD PatientsMarket NeedSickle cell disease is an autosomal recessive blood disorder genes that leads to the affected patient’s hemoglobin is abnormal, causing RBCs to become hard, sickle-shaped, and less efficient at carrying oxygen. There...

Published: 7/8/2019 | Inventor(s): Stella Chou

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Category(s): Diagnostic, Research Tool/Reagent