Search Results - Diagnostic

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Detect Mulitple Types of Epithelial Tumors and Determine Cancer Sage with ONe Biomarker
ZEB1 expression levels predict metastatic potential Market NeedClinicians and pathologists need to determine the stage of cancer progression in a patient to determine the appropriate course of treatment. Currently, there are two methods to determine the stage of a patient’s cancer. The first involves taking a biopsy of the suspected tissue ma...
Published: 5/9/2017   |   Inventor(s): Thomas Genetta
Keywords(s): Epithelial Tumors
Category(s): Diagnostic
Diagnostic Test for Cornelia de Lange Syndrome (CdLS)
Identify Patients and Carriers of CdLS Market NeedThe Cornelia de Lange syndrome (CdLS) is a dominantly inherited multisystem developmental disorder that includes growth and cognitive retardation, upper extremity abnormalities, gastroesophageal dysfunction, cardiac ophthalmologic genitourinary anomalies, hirsutism and characteristic facial features...
Published: 5/9/2017   |   Inventor(s): Ian Krantz
Keywords(s): Cornelia de Lange Syndrome (CdLS)
Category(s): Diagnostic
Diagnostic Test for Alagille Syndrome
Identifies Jagged 1 mutations and intragenic alterations Market NeedAlagille syndrome (AGS) is a highly variable, multi-system, autosomal dominant disorder that affects at least 1 in 70,000 newborns. It is often associated with neonatal jaundice and has traditionally been diagnosed based on bile duct paucity and resultant liver disease, in combinat...
Published: 5/9/2017   |   Inventor(s): Nancy Spinner, Ian Krantz
Keywords(s): Alagille Syndrome (AGS)
Category(s): Diagnostic
A Simple Blood Test for Pancreatic Function
Patients with cystic fibrosis, cancer, and pancreatitisMarket NeedMany disorders, such as cystic fibrosis, pancreatic cancer, pancreatitis, Schwachman syndrome, and hyperparathyroidism, cause abnormal pancreas function. As a result, fatty acids and triglycerides are not properly absorbed into the bloodstream by the pancreas. Treatments for these di...
Published: 5/9/2017   |   Inventor(s): Virginia Stallings
Keywords(s): Pancreatic Function
Category(s): Diagnostic
Detection of HER2 in Urine to Diagnose Lupus Nephritis (LN)
Point-of-care biomarker for Systemic Lupus NephritisMarket NeedSystemic Lupus Erythematosus (SLE) is an autoimmune disease that varies in severity in which the patient’s immune system mistakenly attacks healthy tissues in the body. Lupus Nephritis (LN) is kidney inflammation, which is a complication of SLE that causes decreased kidney functio...
Published: 2/23/2017   |   Inventor(s): Kathleen Sullivan, Ana Patricia Costa Reis
Keywords(s): Chronic Disease, Diagnostics
Category(s): Diagnostic
Non-invasive biomarker specific for Crohn's disease diagnosis
Serum miRNA panel for non-invasive diagnosis and monitoring of Crohn’s diseaseMarket NeedApproximately 1.6 billion people in the US alone have inflammatory bowel disease, which includes Crohn’s disease. These chronic diseases, which have a significant impact on quality of life, can be treated but not cured. According to estimates based ...
Published: 2/3/2017   |   Inventor(s): Joshua Friedman, Adam Zahm, Meena Thayu, Nicholas Hand, Edwin de Zoeten
Keywords(s): Chronic Disease, Diagnostics
Category(s): Diagnostic