Search Results - Diagnostic

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Improved Blood Transfusion Screening with iPSC-derived Reagents
Red Blood Cell (RBC) Reagents with Rare Antigen Phenotypes for Prevention of Alloimmunization Reaction in SCD PatientsMarket NeedSickle cell disease is an autosomal recessive blood disorder genes that leads to the affected patient’s hemoglobin is abnormal, causing RBCs to become hard, sickle-shaped, and less efficient at carrying oxygen. Ther...
Published: 7/9/2018   |   Inventor(s): Stella Chou
Keywords(s):  
Category(s): Diagnostic, Research Tool/Reagent
Quantitative phenotyping to automate diagnosis of autism spectrum disorder (ASD)
Using machine learning to identify features of ASDMarket NeedAutism spectrum disorder is a developmental disorder that affects communication and behavior. Usually, the disorder is first detected through observation within the first 36 months of age looking for specific developmental milestones. Usually, it is the parents who first raise concerns of...
Published: 7/9/2018   |   Inventor(s): Robert Schultz
Keywords(s):  
Category(s): Diagnostic, Medical Device, Software
Malabsorption Blood Test Extension Beyond Pancreatic Based Diagnosis
Fat Malabsorption Diagnostic Drink and Blood TestLess than 72 hours, No Stool Sample RequiredTECHNOLOGY OVERVIEWFat malabsorption results from various diseases such as pancreatitis, pancreatic cancer and cystic fibrosis. If left undiagnosed, fat malabsorption leads to severe malnutrition, nutritional deficiencies, unwanted weight loss and chronic d...
Published: 5/16/2018   |   Inventor(s): Virginia Stallings
Keywords(s):  
Category(s): Diagnostic
Discovery Of Novel CVID Loci Using The Exome SNP Chip Platform
Center for Applied Genomics (CAG) at CHOPThe Center for Applied Genomics is one of the world's largest genetics research programs, and the only center at a pediatric hospital to have large-scale access to high-throughput genotyping technology. There are over 50 active disease projects – both internally and in collaboration with researchers ac...
Published: 2/27/2018   |   Inventor(s): Hakon Hakonarson, Jin Li
Keywords(s):  
Category(s): Diagnostic
Genome- And Phenome-Wide Association Analyses Uncovers MET as a Susceptibility Gene of Cerebral Palsy
Center for Applied Genomics (CAG) at CHOPThe Center for Applied Genomics is one of the world's largest genetics research programs, and the only center at a pediatric hospital to have large-scale access to high-throughput genotyping technology. There are over 50 active disease projects – both internally and in collaboration with researchers ac...
Published: 2/27/2018   |   Inventor(s): Hakon Hakonarson, John Connolly, Jin Li, Frank Mentch
Keywords(s):  
Category(s): Diagnostic
Detect Mulitple Types of Epithelial Tumors and Determine Cancer Sage with ONe Biomarker
ZEB1 expression levels predict metastatic potential Market NeedClinicians and pathologists need to determine the stage of cancer progression in a patient to determine the appropriate course of treatment. Currently, there are two methods to determine the stage of a patient’s cancer. The first involves taking a biopsy of the suspected tissue ma...
Published: 5/9/2017   |   Inventor(s): Thomas Genetta
Keywords(s): Epithelial Tumors
Category(s): Diagnostic
Diagnostic Test for Cornelia de Lange Syndrome (CdLS)
Identify Patients and Carriers of CdLS Market NeedThe Cornelia de Lange syndrome (CdLS) is a dominantly inherited multisystem developmental disorder that includes growth and cognitive retardation, upper extremity abnormalities, gastroesophageal dysfunction, cardiac ophthalmologic genitourinary anomalies, hirsutism and characteristic facial features...
Published: 5/9/2017   |   Inventor(s): Ian Krantz
Keywords(s): Cornelia de Lange Syndrome (CdLS)
Category(s): Diagnostic
Detection of HER2 in Urine to Diagnose Lupus Nephritis (LN)
Point-of-care biomarker for Systemic Lupus NephritisMarket NeedSystemic Lupus Erythematosus (SLE) is an autoimmune disease that varies in severity in which the patient’s immune system mistakenly attacks healthy tissues in the body. Lupus Nephritis (LN) is kidney inflammation, which is a complication of SLE that causes decreased kidney functio...
Published: 2/23/2017   |   Inventor(s): Kathleen Sullivan, Ana Patricia Costa Reis
Keywords(s): Chronic Disease, Diagnostics
Category(s): Diagnostic
Non-invasive biomarker specific for Crohn's disease diagnosis
Serum miRNA panel for non-invasive diagnosis and monitoring of Crohn’s diseaseMarket NeedApproximately 1.6 billion people in the US alone have inflammatory bowel disease, which includes Crohn’s disease. These chronic diseases, which have a significant impact on quality of life, can be treated but not cured. According to estimates based ...
Published: 2/3/2017   |   Inventor(s): Joshua Friedman, Adam Zahm, Meena Thayu, Nicholas Hand, Edwin De Zoeten
Keywords(s): Chronic Disease, Diagnostics
Category(s): Diagnostic